UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q9Z0M6
Entry Name

AGRE5_MOUSE
Protein Name

Adhesion G protein-coupled receptor E5
Primary Gene Name

Adgre5
Organism

Mus musculus (Mouse)
Molecular Function

Receptor
G-protein coupled receptor
Transducer
Membrane Location

Secreted
Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name Adhesion-G protein-coupled receptor CD97(CD97,ADGRE5)
Cell Type
Substrate Description adhesion-class G protein-coupled receptor , leukocyte activation
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase (unkown)
Shedding-related Disease cell receptor (GPCR)
Short Summary of Papers the shedding of the CD97 α-chain induced by CD55 may regulate CD97-CD55-mediated cell adhesion. the shed ectodomains can act as a potent chemoattractant for human endothelial cells and as a proangiogenic factor
Cleavage Information NONE
PMID 15576472 23447688



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		24 533
Transmembrane
 		534 554
Transmembrane
 		563 583
Extracellular
 		584 602
Transmembrane
 		603 623
Transmembrane
 		638 658
Extracellular
 		659 679
Transmembrane
 		680 700
Transmembrane
 		724 744
Extracellular
 		745 752
Transmembrane
 		753 773



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unkown) 15576472    23447688   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA