UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q9Z0J8
Entry Name

NEGR1_RAT
Protein Name

Neuronal growth regulator 1
Primary Gene Name

Negr1
Organism

Rattus norvegicus (Rat)
Molecular Function

Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name neuronal growth regulator 1 (NEGR1)
Cell Type
Substrate Description IgLON protein family,cell adhesion molecules, form homophilic and heterophilic complexes along the cell surface and with juxtaposed cells, modulate adhesion and neurite outgrowth
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype
Sheddase ADAM
Shedding-related Disease cell adhesion molecule (IgLON)
Short Summary of Papers shedding of IgLON may play roles in late stages of cortical neuron outgrowth or synaptogenesis
Cleavage Information ZNo-Human:GPI-anchor
PMID 25538237



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
NO_INFO



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
MEROPS AGQS*VDFP 31 signal peptidase complex (animal) physiologically relevant N-terminal sequencing 10075727   
PAPER No_information ADAM 25538237   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825