|
|
||
|---|---|---|
| UniProt ID |
Q9Y6N7 |
|
| Entry Name |
ROBO1_HUMAN |
|
| Protein Name |
Roundabout homolog 1 |
|
| Primary Gene Name |
ROBO1 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Developmental protein |
|
| Membrane Location |
Cell membrane |
|
|
|
|---|
| Substrate Name | ROBO1 | |
| Cell Type | ||
| Substrate Description | ||
| Substrate Function Category | disease | |
| Substrate Function Subtype | Disease: Cancers (hepatocellular carcinoma) | |
| Sheddase | (unkown), | |
| Shedding-related Disease | cancer (hepatocellular carcinoma) | |
| Short Summary of Papers | ROBO1 is shed into serumin humans, may server as a potential newserologic marker for hepatocellular carcinoma | |
| Cleavage Information | NONE | |
| PMID | 16740745 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
26 | 897 |
|
|
898 | 918 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| ASCENT | MVAV*GEPA | 183 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | AGKY*VCVG | 238 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | YVCV*GTNM | 241 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | PQPA*IFWR | 381 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | IITK*AYLE | 440 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | WQPN*LNSG | 584 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | IEAF*SHAS | 599 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | QISD*PVKT | 650 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | YEIK*ARPF | 750 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | ARPF*FNEF | 754 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | PFFN*EFQG | 756 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | FFNE*FQGA | 757 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | VIPF*LVPG | 841 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | QVSL*AQQI | 886 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | VSLA*QQIS | 887 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | SLAQ*QISD | 888 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | (unkown), | 16740745 | |||||
|
|
|||
|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 17553692 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |