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|---|---|---|
| UniProt ID |
Q9Y5Z0 |
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| Entry Name |
BACE2_HUMAN |
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| Protein Name |
Beta-secretase 2 |
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| Primary Gene Name |
BACE2 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Hydrolase |
|
| Membrane Location |
Cell membrane |
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| Substrate Name | BACE2 | |
| Cell Type | ||
| Substrate Description | beta-secretase mediate proteolytic processing | |
| Substrate Function Category | enzyme | |
| Substrate Function Subtype | ||
| Sheddase | BACE2 | |
| Shedding-related Disease | protease (beta-secretase) | |
| Short Summary of Papers | autolytic processing of BACE2 for proteolytic activity | |
| Cleavage Information | NONE | |
| PMID | 11316808 |
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|---|---|---|
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Start | End |
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21 | 473 |
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|
474 | 494 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| HPRD | GLAL*ALEP | 62 | Beta site APP cleaving enzyme 2 | 11316808 | ||||
| HPRD | GLAL*ALEP | 62 | Beta site APP cleaving enzyme 2 | 11316808 | ||||
| HPRD | GLAL*ALEP | 62 | Beta site APP cleaving enzyme 2 | 11316808 | ||||
| MEROPS | GLAL*ALEP | 62 | memapsin-1 | physiologically relevant | NONE | 11316808 | ||
| PMAP | GLAL*ALEP | 62 | memapsin-1 | This entry is based on an experiment | NONE | |||
| PMAP | GLAL*ALEP | 62 | memapsin-1 | This entry is based on an experiment | 11316808 | |||