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|---|---|---|
| UniProt ID |
Q9UIQ6 |
|
| Entry Name |
LCAP_HUMAN |
|
| Protein Name |
Leucyl-cystinyl aminopeptidase |
|
| Primary Gene Name |
LNPEP |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Hydrolase |
|
| Membrane Location |
Secreted |
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| Substrate Name | Placental leucine aminopeptidase (P-LAP, oxytocinase, LNPEP) | |
| Cell Type | human placenta | |
| Substrate Description | peptide hormone oxytocin degradation (during pregnancy) | |
| Substrate Function Category | enzyme | |
| Substrate Function Subtype | enzyme (aminopeptidase) | |
| Sheddase | ADAM12 | |
| Shedding-related Disease | aminopeptidase | |
| Short Summary of Papers | converted to a soluble form via shedding | |
| Cleavage Information | NONE | |
| PMID | 14751233 |
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Start | End |
|
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111 | 131 |
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132 | 1025 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | IQPF*ATNG | 154 | ADAM12 | NONE | NONE | 14751233 1731608 | ||
| PMAP | RIRP*KLKW | prolyl oligopeptidase | This entry is based on an experiment | NONE | NONE | |||
| PMAP | GFLR*RIRP | prolyl oligopeptidase | This entry is based on an experiment | NONE | NONE | |||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Plasma/Serum | 17553692 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(colorectal carsinoma) | 23585443 | |
| HCSD | cancer(lung adenocarcinoma) | 22896658 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |
| HCSD | cancer(colorectal cancer) | 24681409 | |