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|---|---|---|
| UniProt ID |
Q9UIK5 |
|
| Entry Name |
TEFF2_HUMAN |
|
| Protein Name |
Tomoregulin-2 |
|
| Primary Gene Name |
TMEFF2 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function | ||
| Membrane Location |
Secreted |
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|---|
| Substrate Name | TMEFF2 | |
| Cell Type | ||
| Substrate Description | prostate cancer-specific cell surface marker | |
| Substrate Function Category | disease | |
| Substrate Function Subtype | ||
| Sheddase | ADAM10 | |
| Shedding-related Disease | cancer (prostate cancer) | |
| Short Summary of Papers | TMEFF2 contributes to cell proliferation in an ADAM17-dependent autocrine fashion | |
| Cleavage Information | NONE | |
| PMID | 17942404 |
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|---|
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|---|---|---|
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Start | End |
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41 | 320 |
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321 | 341 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | KLAA*FPTS | 40 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161    | ||
| PMAP | No_information | ADAM17 peptidase | This entry is based on an experiment | Others | 17942404    | |||