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|---|---|---|
| UniProt ID |
Q9NZU1 |
|
| Entry Name |
FLRT1_HUMAN |
|
| Protein Name |
Leucine-rich repeat transmembrane protein FLRT1 |
|
| Primary Gene Name |
FLRT1 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Developmental protein |
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| Membrane Location |
Secreted |
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|---|
| Substrate Name | FLRT1 | |
| Cell Type | ||
| Substrate Description | neurite outgrowth, cell adhesion and cell guidance | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
| Sheddase | metalloprotease | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | all three FLRT ECDs undergo cleavage by metalloproteases and are shed from cultured neurons, | |
| Cleavage Information | NONE | |
| PMID | 21673655 |
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|---|---|---|
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Start | End |
|
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21 | 524 |
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525 | 545 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | metalloprotease | 21673655 | |||||