UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q9JLN6
Entry Name

ADA28_MOUSE
Protein Name

Disintegrin and metalloproteinase domain-containing protein 28
Primary Gene Name

Adam28
Organism

Mus musculus (Mouse)
Molecular Function

Hydrolase
Protease
Metalloprotease
Membrane Location

Membrane



Biological Literature Report of Shedding
Substrate Name ADAM28
Cell Type
Substrate Description
Substrate Function Category
Substrate Function Subtype
Sheddase ADAM28
Shedding-related Disease
Short Summary of Papers autolytic processing of ADAM28 for proteolytic activity
Cleavage Information
PMID 15013428 26554003 23643150



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		196 668
Transmembrane
 		669 689



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PMAP No_information ADAM28 peptidase This_entry_is_based_on_an_experiment. Gel electrophoresis 10794709   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825