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|---|---|---|
| UniProt ID |
Q9HCN6 |
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| Entry Name |
GPVI_HUMAN |
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| Protein Name |
Platelet glycoprotein VI |
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| Primary Gene Name |
GP6 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Receptor |
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| Membrane Location |
Cell membrane |
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| Substrate Name | GPVI | |
| Cell Type | platelet | |
| Substrate Description | platelet hemostasis | |
| Substrate Function Category | blood and homoeostasis | |
| Substrate Function Subtype | platelet; platelet glycoprotein | |
| Sheddase | ADAM10 | |
| Shedding-related Disease | platelet (cell surface protein) | |
| Short Summary of Papers | regulate hemostatic function of platelets | |
| Cleavage Information | NONE | |
| PMID | 24674813 17445093 |
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Start | End |
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21 | 267 |
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268 | 288 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | EFSE*ATAE | 225 | kistomin ( | not physiologically relevant | NONE | 18624975 | ||
| MEROPS | EFSE*ATAE | 225 | kistomin (Calloselasma rhodostoma) | not physiologically relevant | NONE | 18624975 | ||
| MEROPS | TNEV*FTTE | 238 | kistomin (Calloselasma rhodostoma) | not physiologically relevant | NONE | 18624975 | ||
| PAPER | GPAR*QYYT | 263 | ADAM10 | mutagenesis | 24674813 17445093 | |||