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UniProt ID |
Q9HBJ8 |
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Entry Name |
CLTRN_HUMAN |
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Protein Name |
Collectrin |
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Primary Gene Name |
CLTRN |
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Organism |
Homo sapiens (Human) |
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Molecular Function | ||
Membrane Location |
Cell membrane |
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Substrate Name | pancreatic β-cell surface protein (Tmem27) | |
Cell Type | ||
Substrate Description | stimulator of beta cell replication,may regulate β -cell proliferation and insulin secretion | |
Substrate Function Category | insulin | |
Substrate Function Subtype | ||
Sheddase | Bace2 | |
Shedding-related Disease | cell surface protein | |
Short Summary of Papers | membrane-bound form of Tmem27 stimulates β cells replication whereas soluble form of Tmem27 failed to perform same biological results. | |
Cleavage Information | NONE | |
PMID | 22628310 16330324 |
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Start | End |
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15 | 141 |
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142 | 162 |
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Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
PAPER | NNAF*FLND | 116 | Bace2 | 22628310    | ||||
PAPER | AFFL*NDQT | 118 | Bace2 | 22628310    | ||||
PAPER | TLEF*LKIP | 125 | Bace2 | 22628310    |