|
|
||
|---|---|---|
| UniProt ID |
Q9H7M9 |
|
| Entry Name |
VISTA_HUMAN |
|
| Protein Name |
V-type immunoglobulin domain-containing suppressor of T-cell activation |
|
| Primary Gene Name |
VSIR |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Receptor |
|
| Membrane Location |
Cell membrane |
|
|
|
|---|
| Substrate Name | Platelet receptor Gi24 | |
| Cell Type | ||
| Substrate Description | stimulate MMP14-mediated MMP2 activation, contributes to tumor-invasive growth | |
| Substrate Function Category | disease | |
| Substrate Function Subtype | ||
| Sheddase | MT1-MMP, | |
| Shedding-related Disease | cancer (tumor invasion) | |
| Short Summary of Papers | shedding of the GI2 extracellular domain might negatively regulates cellular adhesion to fibronectin | |
| Cleavage Information | NONE | |
| PMID | 20666777 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
33 | 194 |
|
|
195 | 215 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | PVAA*FKVA | 32 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161 | ||
| PAPER | No_information | MT1-MMP, | 20666777 | |||||
|
|
|||
|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||