UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q9ERC8
Entry Name

DSCAM_MOUSE
Protein Name

Down syndrome cell adhesion molecule homolog
Primary Gene Name

Dscam
Organism

Mus musculus (Mouse)
Molecular Function

Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name Down Syndrome Cell Adhesion Molecule(DSCAM)
Cell Type
Substrate Description cell adhesion molecule that plays a role in neuronal self-avoidance. required for normal development of the central nervous system and has been best characterized in the visual system.
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype
Sheddase (unknown)
Shedding-related Disease cell adhesion molecule
Short Summary of Papers DSCAM protein is constitutively cleaved and shed from cells.
Cleavage Information ZNo-Human:
PMID 23300735



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		18 1594
Transmembrane
 		1595 1615



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unknown) 23300735   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825