UniProt Summary
UniProt ID

Q9CYN9

Entry Name

RENR_MOUSE

Protein Name

Renin receptor

Primary Gene Name

Atp6ap2

Organism

Mus musculus (Mouse)

Molecular Function

Receptor

Membrane Location

Postsynaptic cell membrane
Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name renin receptor(Atp6ap2)
Cell Type
Substrate Description renin and prorenin cellular receptor. may mediate renin-dependent cellular responses.
Substrate Function Category blood and homoeostasis
Substrate Function Subtype
Sheddase furin
Shedding-related Disease angiotensin
Short Summary of Papers soluble form of renin receptor generated by furin is detected in plasma and able to bind renin.
Cleavage Information ZNo-Human:
PMID 19380613



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
18 302
Transmembrane
303 323



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER SLVR*KSRT 275 furin mutation 19380613   
PAPER RKSR*TILE 278 furin mutation 19380613   
PAPER No_information furin 19380613   
PaperC No_information BACE1/2 Type I TMP proteomics 23430253   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
PAPER β-Cell 23430253