|
|
||
|---|---|---|
| UniProt ID |
Q9BZM5 |
|
| Entry Name |
ULBP2_HUMAN |
|
| Protein Name |
UL16-binding protein 2 |
|
| Primary Gene Name |
ULBP2 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function | ||
| Membrane Location |
Secreted |
|
|
|
|---|
| Substrate Name | NKG2D ligand (ULBP2) | |
| Cell Type | tumor cells, sera of cancer patients. | |
| Substrate Description | invovled in tumor escape mechanisms | |
| Substrate Function Category | disease | |
| Substrate Function Subtype | Disease: Cancers (cancer escape targeting by NK), immuno therapy | |
| Sheddase | metalloproteinase | |
| Shedding-related Disease | cancer (tumor escape targeting by NK and immuno therapy) | |
| Short Summary of Papers | immune escape involving tumor cell shedding of ULBP2 | |
| Cleavage Information | NONE | |
| PMID | 16510567 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
||
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | metalloproteinase | 16510567 | |||||
|
|
|||
|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(lung adenocarcinoma) | 22896658 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | cancer(Lung adenocarcinoma) | 22985211 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |