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|---|---|---|
| UniProt ID |
Q99MB1 |
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| Entry Name |
TLR3_MOUSE |
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| Protein Name |
Toll-like receptor 3 |
|
| Primary Gene Name |
Tlr3 |
|
| Organism |
Mus musculus (Mouse) |
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| Molecular Function |
RNA-binding |
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| Membrane Location |
Membrane |
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|---|
| Substrate Name | Toll-like receptor 3(TLR3) | |
| Cell Type | ||
| Substrate Description | innate immune response. immune response against pathogens through recognition of molecular patterns specific to microorganisms. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | cathepsin | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | human TLR3 is proteolytically processed to form two fragments in endosomes. | |
| Cleavage Information | ZNo-Human: | |
| PMID | 25305318 |
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|---|---|---|
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Start | End |
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706 | 726 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | SLAS*HPNI | 343 | cathepsin | 25305318 22865861 20855885 | ||||
| PAPER | No_information | (unknown) | 25305318 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||