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| UniProt ID |
Q99K10 |
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| Entry Name |
NLGN1_MOUSE |
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| Protein Name |
Neuroligin-1 |
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| Primary Gene Name |
Nlgn1 |
|
| Organism |
Mus musculus (Mouse) |
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| Molecular Function | ||
| Membrane Location |
Secreted |
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|---|
| Substrate Name | neuroligin-1 (NLG1) | |
| Cell Type | ||
| Substrate Description | postsynaptic adhesion molecule,formation of synapses | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | ||
| Sheddase | ADAM10 | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | proteolytic processing downregulates the cell-surface levels of NLG1, which in turn negatively affects the synaptogenic function | |
| Cleavage Information | ZNo-Human: | |
| PMID | 23083742 |
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Start | End |
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46 | 697 |
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698 | 718 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | PKQQ | 678* | ADAM10 | 23083742 | ||||
| PaperC | No_information | BACE1 | Type I | proteomics | 22728825 | |||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| PAPER | neuron | 22728825 | |