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|---|---|---|
| UniProt ID |
Q96PQ0 |
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| Entry Name |
SORC2_HUMAN |
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| Protein Name |
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain] |
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| Primary Gene Name |
SORCS2 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Postsynaptic cell membrane |
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| Substrate Name | SorCS2, VPS10 domain-containing receptor (SORCS2) | |
| Cell Type | (CHO) Chinese hamster ovary cell | |
| Substrate Description | hormone signaling | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; neuronal receptors | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | cell receptor (VPS10 domain) | |
| Short Summary of Papers | shed versions of sorCS receptors may have wider functions as growth factor-binding proteins that with ligand binding capability | |
| Cleavage Information | NONE | |
| PMID | 16393139 |
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Start | End |
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51 | 1078 |
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1079 | 1099 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | ADAM17 | 16393139 | |||||