|
|
||
|---|---|---|
| UniProt ID |
Q96D42 |
|
| Entry Name |
HAVR1_HUMAN |
|
| Protein Name |
Hepatitis A virus cellular receptor 1 |
|
| Primary Gene Name |
HAVCR1 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Host cell receptor for virus entry |
|
| Membrane Location |
Membrane |
|
|
|
|---|
| Substrate Name | kidney injury molecule-1 (KIM-1,Tim-1) | |
| Cell Type | ||
| Substrate Description | T-helper cell development. regulation of asthma and allergic diseases. kidney injury and repair. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | MT1-MMP, ADAM10, ADAM17 | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | MT1-MMP abrogates KIM-1-mediated negative regulation on cellular function through the cleavage and shedding of KIM-1; soluble TIM-1 might act as negative regulators of cellular TIM-1 | |
| Cleavage Information | NONE | |
| PMID | 22843853 24286866 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
21 | 295 |
|
|
296 | 316 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | G*L | 267 | MT1-MMP | 22843853 | ||||
| PAPER | G*I | 290 | MT1-MMP | 22843853 | ||||