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|---|---|---|
| UniProt ID |
Q92838 |
|
| Entry Name |
EDA_HUMAN |
|
| Protein Name |
Ectodysplasin-A |
|
| Primary Gene Name |
EDA |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Developmental protein |
|
| Membrane Location |
Secreted |
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|---|
| Substrate Name | Ectodysplasin-A (EDA) | |
| Cell Type | ||
| Substrate Description | ectoderm development | |
| Substrate Function Category | development | |
| Substrate Function Subtype | ||
| Sheddase | (unkown) | |
| Shedding-related Disease | ligand (cell surface ligand) | |
| Short Summary of Papers | the shed soluble ectodysplasin is able to interact with EDAR and mediate signals needed for the development of ectodermal appendages | |
| Cleavage Information | NONE | |
| PMID | 11309369 |
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|---|
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|---|---|---|
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Start | End |
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42 | 62 |
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63 | 391 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| HPRD | RNKR*SKSN | 159 | Furin | 11416205 | ||||
| HPRD | RNKR*SKSN | 159 | Furin | 11416205 | ||||
| HPRD | RNKR*SKSN | 159 | Furin | 11416205 | ||||
| MEROPS | RNKR*SKSN | 159 | PCSK7 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | RNKR*SKSN | 159 | PCSK5 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | RNKR*SKSN | 159 | PCSK6 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | RNKR*SKSN | 159 | PCSK4 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | RNKR*SKSN | 159 | PCSK2 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | RNKR*SKSN | 159 | furin | physiologically relevant | NONE | 11416205 | ||
| PMAP | RNKR*SKSN | 159 | furin | This entry is based on an experiment | 11416205 | |||
| PAPER | No_information | (unkown) | 11309369 | |||||