UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q8VHP6
Entry Name

CDHR1_MOUSE
Protein Name

Cadherin-related family member 1
Primary Gene Name

Cdhr1
Organism

Mus musculus (Mouse)
Molecular Function

Receptor
Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name Photoreceptor cadherin (prCAD)
Cell Type
Substrate Description base of rod and cone outer segments, structural integrity
Substrate Function Category cell surface structure
Substrate Function Subtype
Sheddase (suggested)metalloproteinase
Shedding-related Disease outer segments(os), base of rod and cone
Short Summary of Papers prCAD ectodomain cleavage is an integral part of the outer segment assembly process.
Cleavage Information ZNo-Human:
PMID 15284225



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		22 701
Transmembrane
 		702 722



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER SFST*TALL 669 (suggested)metalloproteinase 15284225   
PaperC No_information BACE2 Type I TMP proteomics 23430253   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
PAPER β-Cell 23430253