|
|
||
|---|---|---|
| UniProt ID |
Q8TDQ0 |
|
| Entry Name |
HAVR2_HUMAN |
|
| Protein Name |
Hepatitis A virus cellular receptor 2 |
|
| Primary Gene Name |
HAVCR2 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function | ||
| Membrane Location |
Cell membrane |
|
|
|
|---|
| Substrate Name | T cell immunoglobulin mucin domain 3 (Tim-3) | |
| Cell Type | ||
| Substrate Description | cell surface receptor implicated in modulating innate and adaptive immune responses. | |
| Substrate Function Category | disease | |
| Substrate Function Subtype | ||
| Sheddase | ADAM10 | |
| Shedding-related Disease | infection (HIV) | |
| Short Summary of Papers | shed sTim-3 was found elevated during early and chronic untreated HIV infection, correlated with HIV disease progression | |
| Cleavage Information | NONE | |
| PMID | 25609823 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
22 | 202 |
|
|
203 | 223 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | ADAM10 | 25609823 | |||||
| PAPER | No_information | ADAM10, ADAM17 | 24121505 | |||||