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|---|---|---|
| UniProt ID |
Q8NBJ4 |
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| Entry Name |
GOLM1_HUMAN |
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| Protein Name |
Golgi membrane protein 1 |
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| Primary Gene Name |
GOLM1 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Membrane |
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| Substrate Name | Golgi Phosphoprotein 2 (GOLPH2) | |
| Cell Type | patient-derived xenograft (PDX)-models, colorectal and lung cancer | |
| Substrate Description | ||
| Substrate Function Category | ||
| Substrate Function Subtype | ||
| Sheddase | Unknown | |
| Shedding-related Disease | colorectal and lung cancer | |
| Short Summary of Papers | antibody drug conjugate against GOLPH2 shows high efficacy and improves survival | |
| Cleavage Information | ||
| PMID | 31541350 |
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Start | End |
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13 | 35 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| ASCENT | LQAA*GLPH | 213 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | LQAA*GLPH | 213 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | QAAL*SVSQ | 306 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Saliva | 18361515 | |
| Sys-BodyFluid | Saliva | 16740002 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Tear | 16901338 | |
| Sys-BodyFluid | Urine | 16335936 | |
| Sys-BodyFluid | Urine | 16948836 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(urothelial carcinoma) | 23591195 | |
| HCSD | cancer(glioblastoma multiforme) | 21574646 | |
| HCSD | cancer(breast cancer) | 24505115 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | cancer(metastatic non-small-cell lung cancer) | 24667143 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |