UniProt Summary
UniProt ID

Q8BSU2

Entry Name

CXL16_MOUSE

Protein Name

C-X-C motif chemokine 16

Primary Gene Name

Cxcl16

Organism

Mus musculus (Mouse)

Molecular Function

Cytokine

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name CXCL16
Cell Type endothelial cell, monocytes
Substrate Description Leukocyte Recruitment, Chemokine recruitment of leukocytes, Firm adhesion and locomotion to the endothelial cell junction
Substrate Function Category Immune and Inflammation
Substrate Function Subtype Immune and Inflammation; cytokine
Sheddase ADAM10
Shedding-related Disease cytokine
Short Summary of Papers release soluble chemokine,de-adhesion, soluble chemoattractant, decreased scavenger receptor activity, decreased endothelial
Cleavage Information NONE
PMID 16565325 23428418 18951988



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
27 201
Transmembrane
202 222



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information ADAM10 15004171   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825