UniProt Summary
UniProt ID

Q7TSK2

Entry Name

SEZ6_MOUSE

Protein Name

Seizure protein 6

Primary Gene Name

Sez6

Organism

Mus musculus (Mouse)

Molecular Function

Membrane Location

Secreted
Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name Seizure protein 6
Cell Type primary neurons
Substrate Description
Substrate Function Category
Substrate Function Subtype
Sheddase BACE1
Shedding-related Disease
Short Summary of Papers Seizure protein 6 is one of the enriched secreted proteins released by BACE1 in neurons.
Cleavage Information
PMID 22728825



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
20 922
Transmembrane
923 943



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PaperC No_information BACE1 Type I proteomics,western blot 22728825   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
PAPER neuron 22728825