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|---|---|---|
| UniProt ID |
Q6UXM1 |
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| Entry Name |
LRIG3_HUMAN |
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| Protein Name |
Leucine-rich repeats and immunoglobulin-like domains protein 3 |
|
| Primary Gene Name |
LRIG3 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Developmental protein |
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| Membrane Location |
Cell membrane |
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| Substrate Name | LRIG3 | |
| Cell Type | HeLa (ATCC); human embryonic kidney (HEK) 293-FT (Invitrogen) | |
| Substrate Description | ||
| Substrate Function Category | ||
| Substrate Function Subtype | ||
| Sheddase | BACE1 | |
| Shedding-related Disease | ||
| Short Summary of Papers | BACE1 expression produces ectodomain of LRIG3. | |
| Cleavage Information | ||
| PMID | 20041192 |
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Start | End |
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810 | 830 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | LGRA*GRSD | 24 | unknown peptidase | physiologically relevant | Mass spectroscopy | 26796116 | ||