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| UniProt ID |
Q6UXK5 |
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| Entry Name |
LRRN1_HUMAN |
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| Protein Name |
Leucine-rich repeat neuronal protein 1 |
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| Primary Gene Name |
LRRN1 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Membrane |
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| Substrate Name | Neuronal leucine-rich repeat 1 | |
| Cell Type | neuroblastoma cells | |
| Substrate Description | ||
| Substrate Function Category | ||
| Substrate Function Subtype | ||
| Sheddase | Unknown | |
| Shedding-related Disease | neuroblastoma | |
| Short Summary of Papers | NLRR1 and anaplastic lymphoma kinase (ALK) have mutually exclusive expression in human neuroblastoma; in addition, NLRR1 ectodomain inhibits ALK physically | |
| Cleavage Information | ||
| PMID | 27604320 |
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Start | End |
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26 | 631 |
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632 | 652 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | LTES*SIQN | 25 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161 | ||
| MEROPS | TNNP*KLSY | 323 | peptidyl-Lys metallopeptidase | not physiologically relevant | Mass spectroscopy | NONE | ||
| MEROPS | AIYQ*KTVE | 354 | peptidyl-Lys metallopeptidase | not physiologically relevant | Mass spectroscopy | NONE | ||