UniProt Summary
UniProt ID

Q6U7R4

Entry Name

TIMD4_MOUSE

Protein Name

T-cell immunoglobulin and mucin domain-containing protein 4

Primary Gene Name

Timd4

Organism

Mus musculus (Mouse)

Molecular Function

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name Tim-4
Cell Type
Substrate Description ligand for HAVCR1/TIMD1. T-cell proliferation and lymphotoxin signaling
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase ADAM10, ADAM17
Shedding-related Disease cell receptor
Short Summary of Papers the shed soluble TIM-4 might act as negative regulators of cellular TIM-4
Cleavage Information ZNo-Human:
PMID 24286866



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
23 279
Transmembrane
280 300



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information ADAM10,ADAM17 24286866   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA