|
|
||
|---|---|---|
| UniProt ID |
Q6GTX8 |
|
| Entry Name |
LAIR1_HUMAN |
|
| Protein Name |
Leukocyte-associated immunoglobulin-like receptor 1 |
|
| Primary Gene Name |
LAIR1 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Receptor |
|
| Membrane Location |
Cell membrane |
|
|
|
|---|
| Substrate Name | Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) | |
| Cell Type | ||
| Substrate Description | inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | LAIR-1 can be released when lymphocytes are activated and the shed sLAIR-1 may be used as a predictor for monitoring immune reaction in some virus infections and organ transplants | |
| Cleavage Information | NONE | |
| PMID | 15350516 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
22 | 165 |
|
|
166 | 186 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | EVTY*AQLD | 251 | RC1339 g.p. (Rickettsia conorii) | not physiologically relevant | Mass spectroscopy | 25144529 | ||
| PAPER | No_information | (unknown) | 15350516 | |||||