|
|
||
|---|---|---|
| UniProt ID |
Q6EMK4 |
|
| Entry Name |
VASN_HUMAN |
|
| Protein Name |
Vasorin |
|
| Primary Gene Name |
VASN |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function | ||
| Membrane Location |
Secreted |
|
|
|
|---|
| Substrate Name | vasorin | |
| Cell Type | ||
| Substrate Description | inhibitor of TGF-beta signaling | |
| Substrate Function Category | growth factor & growth hormone | |
| Substrate Function Subtype | cell surface protein (TGF- β binding protein) | |
| Sheddase | ADAM17, | |
| Shedding-related Disease | growth factor binding protein | |
| Short Summary of Papers | soluble form of VASN inhibits TGFβ signaling | |
| Cleavage Information | NONE | |
| PMID | 21170088 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
24 | 575 |
|
|
576 | 596 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | GVQG*CPSG | 23 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | QGCP*SGCQ | 25 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | ADAM17, | 21170088 | |||||
|
|
|||
|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Amniotic fluid | 17373841 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Cerebrospinal fluid | 14998169 | |
| Sys-BodyFluid | Urine | 16569576 | |
| Sys-BodyFluid | Urine | 16335936 | |
| Sys-BodyFluid | Urine | 16281181 | |
| Sys-BodyFluid | Urine | 16948836 | |
| Sys-BodyFluid | Plasma/Serum | 18793429 | |
| Sys-BodyFluid | Plasma/Serum | 18795103 | |
| Sys-BodyFluid | Plasma/Serum | 17877382 | |
| Sys-BodyFluid | Plasma/Serum | 16944932 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 16739989 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(urothelial carcinoma) | 23591195 | |
| HCSD | cancer(glioblastoma multiforme) | 21574646 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(Lung adenocarcinoma) | 22985211 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(Glioblastoma) | 23483059 | |
| locate | 17986452 | ||
| HCSD | cancer(lung cancer) | 21806062 | |