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|---|---|---|
| UniProt ID |
Q62179 |
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| Entry Name |
SEM4B_MOUSE |
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| Protein Name |
Semaphorin-4B |
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| Primary Gene Name |
Sema4b |
|
| Organism |
Mus musculus (Mouse) |
|
| Molecular Function |
Developmental protein |
|
| Membrane Location |
Membrane |
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|---|
| Substrate Name | semaphorin-4B (SEMA4B) | |
| Cell Type | pancreatic β-cells | |
| Substrate Description | ||
| Substrate Function Category | ||
| Substrate Function Subtype | ||
| Sheddase | BACE1, BACE2 | |
| Shedding-related Disease | ||
| Short Summary of Papers | SEMA4B is a substrate of BACE2 and BACE1 in pancreatic beta-cells. | |
| Cleavage Information | ||
| PMID | 23430253 |
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|---|---|---|
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Start | End |
|
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31 | 703 |
|
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704 | 724 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | TVSS*FQGN | 196 | matrix metallopeptidase-2 | not physiologically relevant | Mass spectroscopy | 20305283 | ||
| PaperC | No_information | BACE2 | Type I TMP | proteomics, Western blot | 23430253 | |||