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| UniProt ID |
Q62165 |
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| Entry Name |
DAG1_MOUSE |
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| Protein Name |
Dystroglycan |
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| Primary Gene Name |
Dag1 |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function | ||
| Membrane Location |
Postsynaptic cell membrane |
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| Substrate Name | Dystroglycan | |
| Cell Type | ||
| Substrate Description | provide link between the ECM and cortical cytoskeleton | |
| Substrate Function Category | cell surface structure | |
| Substrate Function Subtype | cell adhesion molecule (dystrophin complex) | |
| Sheddase | MMP2, MMP9 | |
| Shedding-related Disease | dystroglycan complex | |
| Short Summary of Papers | MMPs degrade DG complex components and disrupt the link between the ECM and cell membrane, presumed to have a deleterious effect on the stability of cell membrane | |
| Cleavage Information | NONE | |
| PMID | 19946898 16701552 |
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Start | End |
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652 | 751 |
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752 | 772 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | ENGA*LLSW | 254 | matrix metallopeptidase-2 | not physiologically relevant | Mass spectroscopy | NONE | ||
| MEROPS | LLSW*KLGC | 258 | matrix metallopeptidase-2 | not physiologically relevant | Mass spectroscopy | 20305283 | ||
| PMAP | No_information | matrix metallopeptidase-2 | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 16585265 | |||