UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q61830
Entry Name

MRC1_MOUSE
Protein Name

Macrophage mannose receptor 1
Primary Gene Name

Mrc1
Organism

Mus musculus (Mouse)
Molecular Function

Receptor
Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name mannose receptor (MR)
Cell Type
Substrate Description endocytosis of glycoproteins by macrophages
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase metalloprotease
Shedding-related Disease cell receptor
Short Summary of Papers the shed soluble MR (sMR) maintained its ability to mannosylated ligand, might plays a role in the transport of mannosylated proteins from the site of inflammation to other parts of the body
Cleavage Information NONE
PMID 10545481 9722572



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		20 1388
Transmembrane
 		1389 1409



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information metalloprotease 9722572   
PAPER No_information (unkown) 26316303   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA