UniProt Summary
UniProt ID

Q60625

Entry Name

ICAM5_MOUSE

Protein Name

Intercellular adhesion molecule 5

Primary Gene Name

Icam5

Organism

Mus musculus (Mouse)

Molecular Function

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name intercellular adhesion molecule-5 (ICAM-5)
Cell Type
Substrate Description ligands for the leukocyte adhesion protein LFA-1
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype
Sheddase MMP
Shedding-related Disease cell adhesion molecule
Short Summary of Papers ICAM-5 shedding by MMPs suggested that the shedding of molecules may regulate neuronal activity via inhibit dendritic spine enlargement.
Cleavage Information ZNo-Human:
PMID 17901375



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
32 833
Transmembrane
834 854



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information MMP 17901375   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA