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|---|---|---|
| UniProt ID |
Q5QNS5 |
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| Entry Name |
HAVR1_MOUSE |
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| Protein Name |
Hepatitis A virus cellular receptor 1 homolog |
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| Primary Gene Name |
Havcr1 |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function | ||
| Membrane Location |
Membrane |
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|---|
| Substrate Name | kidney injury molecule-1 (KIM-1,Tim-1) | |
| Cell Type | ||
| Substrate Description | T-helper cell development. regulation of asthma and allergic diseases. kidney injury and repair. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | MT1-MMP, ADAM10, ADAM17 | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | MT1-MMP abrogates KIM-1-mediated negative regulation on cellular function through the cleavage and shedding of KIM-1; soluble TIM-1 might act as negative regulators of cellular TIM-1 | |
| Cleavage Information | NONE | |
| PMID | 22843853 24286866 |
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Start | End |
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22 | 237 |
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238 | 258 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | ADAM10,ADAM17 | 24286866 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| NO_DATA | NO_DATA | NO_DATA | |