UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q5KU26
Entry Name

COL12_HUMAN
Protein Name

Collectin-12
Primary Gene Name

COLEC12
Organism

Homo sapiens (Human)
Molecular Function

Receptor
Membrane Location

Membrane



Biological Literature Report of Shedding
Substrate Name Collectin-12 (CL-12)
Cell Type CHO cells; human umbilical cord plasma
Substrate Description
Substrate Function Category
Substrate Function Subtype
Sheddase (unknown)
Shedding-related Disease
Short Summary of Papers Soluble CL-12 might be a novel mechanism as an alternative pathway of complement.
Cleavage Information
PMID 26290605



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Transmembrane
 		38 58
Extracellular
 		59 742



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825