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|---|---|---|
| UniProt ID |
Q2VLH6 |
|
| Entry Name |
C163A_MOUSE |
|
| Protein Name |
Scavenger receptor cysteine-rich type 1 protein M130 |
|
| Primary Gene Name |
Cd163 |
|
| Organism |
Mus musculus (Mouse) |
|
| Molecular Function | ||
| Membrane Location |
Secreted |
|
|
|
|---|
| Substrate Name | Scavenger receptor cysteine-rich type 1 protein M130(CD163) | |
| Cell Type | ||
| Substrate Description | endocytosis of hemoglobin/haptoglobin complexes by macrophages | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | ADAM17 | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | the shed sCD163 may be regarded as a surrogate marker of the rapidly cleared TNF-α released from macrophages in inflammation | |
| Cleavage Information | NONE | |
| PMID | 20807704 |
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|---|
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|---|---|---|
|
|
Start | End |
|
|
39 | 1045 |
|
|
1046 | 1066 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | TGHP*TLTA | 1044 | metalloprotease | 16542157 | ||||
|
|
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| NO_DATA | NO_DATA | NO_DATA | |