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UniProt ID |
Q16790 |
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Entry Name |
CAH9_HUMAN |
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Protein Name |
Carbonic anhydrase 9 |
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Primary Gene Name |
CA9 |
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Organism |
Homo sapiens (Human) |
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Molecular Function |
Lyase |
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Membrane Location |
Cell membrane |
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Substrate Name | carbonic anhydrase IX | |
Cell Type | ||
Substrate Description | hydration of carbon dioxide | |
Substrate Function Category | disease;enzyme | |
Substrate Function Subtype | ||
Sheddase | ADAM17 | |
Shedding-related Disease | cancer (renal carcinoma);anhydrase | |
Short Summary of Papers | cleavage of CA IX ectodomain is a regulated process that responds to physiological factors and signal transduction stimuli; soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients. | |
Cleavage Information | NONE | |
PMID | 9439598 |
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Start | End |
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38 | 414 |
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415 | 435 |
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Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
MEROPS | PVHP*QRLP | 37 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161    | ||
PAPER | REED*PPGE | 76 | UNKNOWN | Mass spectrometry | 33796845    | |||
PAPER | No_information | ADAM17 | 9439598    |