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|---|---|---|
| UniProt ID |
Q14626 |
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| Entry Name |
I11RA_HUMAN |
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| Protein Name |
Interleukin-11 receptor subunit alpha |
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| Primary Gene Name |
IL11RA |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Receptor |
|
| Membrane Location |
Secreted |
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|---|
| Substrate Name | IL-11R | |
| Cell Type | ||
| Substrate Description | receptor for interleukin-11. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | ADAM10 | |
| Shedding-related Disease | cytokine receptor | |
| Short Summary of Papers | IL-11R is a substrate for ADAM10. The soluble IL-11R binds IL-11 and initiates IL-11 trans-signaling. | |
| Cleavage Information | NONE | |
| PMID | 26876177 |
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Start | End |
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24 | 370 |
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371 | 391 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | H---S (region) | 353* | ADAM10 | 26876177 | ||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||