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| UniProt ID |
Q14517 |
|
| Entry Name |
FAT1_HUMAN |
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| Protein Name |
Protocadherin Fat 1 |
|
| Primary Gene Name |
FAT1 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Cell membrane |
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|---|
| Substrate Name | protocadherin Fat1 | |
| Cell Type | ||
| Substrate Description | cerebral development,glomerular slit formation,developmental processes | |
| Substrate Function Category | disease | |
| Substrate Function Subtype | ||
| Sheddase | ADAM10 | |
| Shedding-related Disease | cancer (pancreatic cancer) | |
| Short Summary of Papers | shed soluble fat1 may be a marker for patient (pancreatic cancer) for patient monitoring complementing carbohydrate antigen 19-9 (CA19-9) | |
| Cleavage Information | NONE | |
| PMID | 15922730 24625754 |
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Start | End |
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22 | 4181 |
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4182 | 4202 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | QVMY*SLDQ | 2846 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | PPFF*FTIV | 3477 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | PNQY*VSTP | 4170 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | ADAM10 | 15922730 24625754 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Plasma/Serum | 16878292 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 17553692 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(colorectal carsinoma) | 23585443 | |
| HCSD | cancer(lung adenocarcinoma) | 22896658 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |
| HCSD | cancer(colorectal cancer) | 24681409 | |
| HCSD | cancer(colorectal cancer) | 25216327 | |