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| UniProt ID |
Q13740 |
|
| Entry Name |
CD166_HUMAN |
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| Protein Name |
CD166 antigen |
|
| Primary Gene Name |
ALCAM |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Secreted |
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| Substrate Name | ALCAM(CD166) | |
| Cell Type | epithelial ovarian cancer (EOC) | |
| Substrate Description | cell migration, cell morphogenesis, neurite outgrowth, T-cell activation and proliferation | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | cell adhesion molecule | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | shedding and release of sALCAM adhesive functions may play a role in cell motility and invasiveness. | |
| Cleavage Information | NONE | |
| PMID | 18171982 |
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Start | End |
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28 | 527 |
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528 | 549 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | PGLG*WYTV | 27 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | LGWY*TVNS | 29 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | YTVN*SAYG | 32 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | STKK*SVQY | 76 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | FVCM*LVTE | 114 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | IVSK*ALFL | 142 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | SYPD*GNIT | 165 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | KEMD*PVTQ | 193 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | LYTM*TSTL | 201 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | KTTK*ADIQ | 211 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | QMPF*TCSV | 218 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | MPFT*CSVT | 219 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | PFTC*SVTY | 220 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | PFTC*SVTY | 220 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | CSVT*YYGP | 223 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | CLGN*GNPP | 273 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | ITVH*YLDL | 330 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | TVHY*LDLS | 331 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | RQIG*DALP | 347 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | QIGD*ALPV | 348 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | PVSC*TISA | 354 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | LNVS*AISI | 501 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | NVSA*ISIP | 502 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | VSAI*SIPE | 503 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | VSAI*SIPE | 503 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | EADE*ISDE | 513 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | IVVG*LLLA | 535 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PMAP | No_information | ADAM10 peptidase | This entry is based on an experiment | Gel electrophoresis | 16782893 | |||
| PMAP | No_information | ADAM17 peptidase | This entry is based on an experiment | Gel electrophoresis | 16782893 | |||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| PAPER | platelet | 20962327 | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17853512 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 16739989 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colon tumor) | 23684732 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(head and neck cancer) | 21598386 | |
| HCSD | cancer(head and neck squamous cell carcinoma) | 22918226 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | cancer(gastric cancer) | 22204653 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |