UniProt Summary
UniProt ID

Q13261

Entry Name

I15RA_HUMAN

Protein Name

Interleukin-15 receptor subunit alpha

Primary Gene Name

IL15RA

Organism

Homo sapiens (Human)

Molecular Function

Receptor

Membrane Location

Secreted
Membrane




Biological Literature Report of Shedding
Substrate Name IL-15R
Cell Type lymphocytes
Substrate Description Leukocyte Recruitment - Cytokines and cytokine receptors involved in cell-cell communication, including firm adhesion
Substrate Function Category Immune and Inflammation
Substrate Function Subtype Immune and Inflammation; cytokine receptor
Sheddase ADAM17
Shedding-related Disease cytokine receptor
Short Summary of Papers soluble IL-15 antagonist, enhanced proinflammatory cytokines
Cleavage Information NONE
PMID 16565325 15265897



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
31 205
Transmembrane
206 228



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PMAP No_information Metallopeptidase This entry is based on an experiment Gel electrophoresis 15265897   
PMAP No_information Metallopeptidase This entry is based on an experiment Gel electrophoresis 15265897   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825