UniProt Summary
UniProt ID

Q13018

Entry Name

PLA2R_HUMAN

Protein Name

Secretory phospholipase A2 receptor

Primary Gene Name

PLA2R1

Organism

Homo sapiens (Human)

Molecular Function

Receptor

Membrane Location

Secreted
Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name phospholipase A2 receptor
Cell Type HEK293 cells
Substrate Description
Substrate Function Category
Substrate Function Subtype
Sheddase Unknown
Shedding-related Disease fibrosis, inflammation and cancer
Short Summary of Papers existence of immunoreactive PLA2R in human plasma is proved
Cleavage Information
PMID 29791208



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
21 1397
Transmembrane
1398 1418



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
MEROPS RGCA*EGVA 20 unknown peptidase physiologically relevant Mass spectroscopy 26796116   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
Sys-BodyFluid Plasma/Serum 12917320
Sys-BodyFluid Plasma/Serum 16104056
Sys-BodyFluid Plasma/Serum 14718574
HCSD cancer(ovarian cancer) 22623176