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|---|---|---|
| UniProt ID |
Q12907 |
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| Entry Name |
LMAN2_HUMAN |
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| Protein Name |
Vesicular integral-membrane protein VIP36 |
|
| Primary Gene Name |
LMAN2 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Membrane |
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| Substrate Name | VIP36 | |
| Cell Type | ||
| Substrate Description | lectin domain-containing transmembrane protein. cargo receptor for Golgi-to-endoplasmic reticulum transport, | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | ADAM | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | the shedding of VIP36 on the cell surface is required for the regulation of phagocytosis in macrophages | |
| Cleavage Information | NONE | |
| PMID | 22016386 |
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Start | End |
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323 | 345 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| ASCENT | LGSV*TADI | 42 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | SVTA*DITD | 44 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | SVTA*DITD | 44 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | SVTA*DITD | 44 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | SVTA*DITD | 44 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| MEROPS | SVTA*DITD | 44 | signal peptidase complex (animal) | physiologically relevant | Mass spectroscopy | 12665801 | ||
| PAPER | SVNF*LKSP | 298 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | ADAM | 22016386 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17853512 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Urine | 17022654 | |
| Sys-BodyFluid | Urine | 11680902 | |
| Sys-BodyFluid | Urine | 16335936 | |
| Sys-BodyFluid | Urine | 15048996 | |
| Sys-BodyFluid | Urine | 16281181 | |
| Sys-BodyFluid | Urine | 16948836 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colon tumor) | 23684732 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(head and neck squamous cell carcinoma) | 22918226 | |
| HCSD | cancer(urothelial carcinoma) | 23591195 | |
| HCSD | cancer(glioblastoma multiforme) | 21574646 | |
| HCSD | cancer(lung adenocarcinoma) | 22896658 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(gastric cancer) | 22204653 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |