UniProt Summary
UniProt ID

Q12866

Entry Name

MERTK_HUMAN

Protein Name

Tyrosine-protein kinase Mer

Primary Gene Name

MERTK

Organism

Homo sapiens (Human)

Molecular Function

Kinase
Tyrosine-protein kinase
Transferase
Receptor

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name MERTK
Cell Type
Substrate Description receptor tyrosine kinase
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase (unkown)
Shedding-related Disease cell receptor
Short Summary of Papers cardiomyocytes induce MERTK shedding to reduce phagocytosis
Cleavage Information NONE
PMID 26316303



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
21 505
Transmembrane
506 526



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unkown) 26316303   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
HCSD cancer(prostate cancer) 22908226
HCSD cancer(ovarian cancer) 23805888