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|---|---|---|
| UniProt ID |
Q12864 |
|
| Entry Name |
CAD17_HUMAN |
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| Protein Name |
Cadherin-17 |
|
| Primary Gene Name |
CDH17 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Cell membrane |
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|---|
| Substrate Name | cadherin-17 (CDH17) | |
| Cell Type | ||
| Substrate Description | calcium-dependent cell adhesion proteins. liver-intestine cadherin, morphological organization of liver and intestine. | |
| Substrate Function Category | disease | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | cancer (colon cancer) | |
| Short Summary of Papers | shedding in metastatic cells makes CDH17 a candidate biomarker for detection in biofluids (serum or plasma) of colon cancer patients. | |
| Cleavage Information | NONE | |
| PMID | 25336636 |
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|---|---|---|
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Start | End |
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23 | 787 |
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788 | 808 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | (unknown) | 25336636 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| Sys-BodyFluid | Urine | 16948836 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(colon tumor) | 23684732 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |