UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q08857
Entry Name

CD36_MOUSE
Protein Name

Platelet glycoprotein 4
Primary Gene Name

Cd36
Organism

Mus musculus (Mouse)
Molecular Function

Receptor
Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name GPIV (CD36)
Cell Type
Substrate Description platelet glycoprotein. receptor for a broad range of ligands involved in angiogenesis, inflammatory response, fatty acid metabolism
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase ADAM17
Shedding-related Disease cell receptor
Short Summary of Papers ADAM17-mediated proteolysis of CD36 control apoptotic cell phagocytosis, inflammation and its resolution.
Cleavage Information ZNo-Human:
PMID 8655633



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Transmembrane
 		8 29
Extracellular
 		30 439
Transmembrane
 		440 461



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER AVFG*GILM 23 ADAM17 8655633   
PAPER IKRE*VVLE 41 ADAM17 8655633   
PAPER GDEK*AEMF 426 ADAM17 8655633   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA