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|---|---|---|
| UniProt ID |
Q05910 |
|
| Entry Name |
ADAM8_MOUSE |
|
| Protein Name |
Disintegrin and metalloproteinase domain-containing protein 8 |
|
| Primary Gene Name |
Adam8 |
|
| Organism |
Mus musculus (Mouse) |
|
| Molecular Function |
Hydrolase |
|
| Membrane Location |
Membrane |
|
|
|
|---|
| Substrate Name | ADAM8 | |
| Cell Type | ||
| Substrate Description | diverse cellular process regulated by proteolytic cleavage | |
| Substrate Function Category | enzyme | |
| Substrate Function Subtype | enzyme (protease) | |
| Sheddase | ADAM8 | |
| Shedding-related Disease | protease (metalloproteinase) | |
| Short Summary of Papers | autolytic processing of ADAM8 for proteolytic activity | |
| Cleavage Information | NONE | |
| PMID | 12372841 |
|
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|---|
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|---|---|---|
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Start | End |
|
|
17 | 658 |
|
|
659 | 683 |
|
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | NRFV*GGPV | 401 | ADAM8 peptidase | physiologically relevant | NONE | 12372841 | ||
| PMAP | NRFV*GGPV | 401 | ADAM8 peptidase | This_entry_is_based_on_an_experiment. | N-terminal sequencing | 12372841 14761956 | ||
|
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||