UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q03137
Entry Name

EPHA4_MOUSE
Protein Name

Ephrin type-A receptor 4
Primary Gene Name

Epha4
Organism

Mus musculus (Mouse)
Molecular Function

Tyrosine-protein kinase
Developmental protein
Transferase
Kinase
Receptor
Membrane Location

Postsynaptic cell membrane
Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name EphA4 receptor(Epha4)
Cell Type
Substrate Description receptor tyrosine kinase which binds membrane-bound ephrin family ligands,neuron development, axon guidance
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype
Sheddase (unknown)
Shedding-related Disease cell receptor (Eph)
Short Summary of Papers shedding of EphA4 rceptor regulates spinal motor axon guidance
Cleavage Information ZNo-Human:
PMID 25264256



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		20 547
Transmembrane
 		548 569



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unknown) 25264256   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825