UniProt Summary
UniProt ID

Q01344

Entry Name

IL5RA_HUMAN

Protein Name

Interleukin-5 receptor subunit alpha

Primary Gene Name

IL5RA

Organism

Homo sapiens (Human)

Molecular Function

Receptor

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name IL-5Ralpha
Cell Type
Substrate Description receptor for interleukin-5.
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase MMP
Shedding-related Disease cytokine receptor
Short Summary of Papers IL-5 down-Modulates IL-5Rα via a proteinase-mediated process and results in the release of sIL-5Rα.
Cleavage Information NONE
PMID 12444155



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
21 342
Transmembrane
343 362



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information MMP 12444155   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825
Sys-BodyFluid Plasma/Serum 18795103
locate 17986452