UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

Q00993
Entry Name

UFO_MOUSE
Protein Name

Tyrosine-protein kinase receptor UFO
Primary Gene Name

Axl
Organism

Mus musculus (Mouse)
Molecular Function

Kinase
Tyrosine-protein kinase
Transferase
Receptor
Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name Axl
Cell Type
Substrate Description regulating many physiological processes in cell survival, cell proliferation, migration and differentiation
Substrate Function Category enzyme
Substrate Function Subtype receptor (Tyrosine-protein kinase receptor)
Sheddase ADAM10
Shedding-related Disease receptor tyrosine kinase
Short Summary of Papers produce soluble form of Axl by proteolytic cleavage
Cleavage Information NONE
PMID 7822279 16227584



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		19 445
Transmembrane
 		446 466



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information ADAM10 16227584   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA